A Research Fellow position is available in the laboratory of Prof Peter Preiser, School of Biological Sciences, Nanyang Technological University, Singapore. The project will focus on elucidating the signaling events in the erythrocyte during Plasmodium falciparum and Plasmodium knowlesi merozoite invasion. Notably, the study aims to examine the conservation of signaling pathways in erythrocytes between the invasion processes of P. falciparum and P. knowlesi. This involves the functional validation of host signaling proteins, characterization of parasite invasion proteins that trigger host signaling, and quantification of intracellular signaling, using a range of biochemical, cellular and molecular biology techniques.
The candidate will work with P. falciparum and P. knowlesi parasites to identify and characterize the parasite ligand(s) that trigger host cell signaling in erythrocytes and identify the erythrocyte signaling complex that promotes host signaling during merozoite invasion. These proteins will be validated using a range of biochemical, cellular and molecular biological techniques.
PhD in Biosciences with focus on cell / molecular biology
At least 2 years prior experience in malaria parasite research is preferred
Experience in parasite cell culture is essential
Experience in biochemical, cellular and molecular biology methods, such as ELISA, fluorescent microscopy, plasmid cloning and western blotting, is critical
Experience in cellular signaling and hematology work is a bonus.
Excellent communication (written and verbal) skills
Strong interpersonal skills for collaborative working, to be self-motivated, well-organized and focused
The School of Biological Sciences seeks a diverse and inclusive workforce and is committed to equality of opportunity. We welcome applications from all and recruit on the basis of merit, regardless of age, race, gender, religion, marital status and family responsibilities, or disability.
We regret that only shortlisted candidates will be notified.
Hiring Institution: NTU
In line with Singapore’s nationwide Vaccination-Differentiated Safe Management Measures (VDS), employees must be fully vaccinated to return to the workplace, unless certified to be medically ineligible. For Information on VDS, please click [ Link removed ] .
- Cell Cultures
- Cloning (Biology)
- Enzyme Linked Immunosorbent Assay (Elisa)